CIMT and Plaque Assessment Findings in Subjects Undergoing Stress Echocardiography for Risk Stratification
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 13-008535
NCT ID: NCT02245048
Sponsor Protocol Number: 13-008535
About this study
The purpose of this research study is to determine if carotid artery ultrasound scanning can provide additional information for determining cardiovascular risk in patients.
Patients who agree to participate wil undergo non-invasive carotid intima-media thickness (CIMT) measurement and plaque assessment. Findings of CIMT will be compared to results of patient standard of care stress echocardiogram (SE) and of diastolic function.
We hypothesize tht 1) in patients undergoing SE for inappropriate or uncertain indications, CIMT and plaque assessment will provide useful risk stratification beyond use of traditional risk factors; 2) CIMT findings will correlate with results of SE in terms of exercise capacity and 3) Exercise capacity will correlate with diastolic function.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Asymptomatic
- No prior cardiac history (MI, PTCA, CABG, angina)
- No peripheral vascular disease
- No history of stroke or TIA
- Statins, antihypertensives, ASA treatment OK
Exclusion Criteria:
- History of CAD, CABG, PTCA, coronary or peripheral stenting
- History of stroke/TIA/peripheral vascular disease
- Inability to exercise on the treadmill
- Unwilling/unable to sign informed consent
- History of neck radiation or neck surgery or inability to obtain neck images
- End stage renal disease
- Preoperative evaluation
- History of chest pain
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
More information
Publications
Publications are currently not available