Omega-3 Fatty Acids to Combat Sarcopenia
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-000639
NCT ID: NCT02103842
Sponsor Protocol Number: 14-000639
About this study
The purpose of this study is to determine how omega-3 fatty acids influence muscle protein metabolism and mitochondrial physiology in the context of human aging.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age 18-35 or 65-85 years
Exclusion Criteria:
- Current use of omega-3 nutritional supplements
- Fasting plasma glucose ≥126 mg/dL
- Active coronary artery disease
- Participation in structured exercise (>3 times per week for 30 minutes or longer)
- Smoking
- Medications known to affect muscle metabolism (e.g., beta blockers, corticosteroids, tricyclic-antidepressants, benzodiazepines, opiates, barbiturates, anticoagulants)
- Renal failure (serum creatinine > 1.5mg/dl)
- Chronic active liver disease (Bilirubin > 17mmol/L, AST>144IU/L, or ALT>165IU/L)
- Anti-coagulant therapy (warfarin/heparin)
- INR >3
- Use of systemic glucocorticoids
- Chronic use of NSAIDS or aspirin
- Pregnancy or breastfeeding
- Alcohol consumption greater than 2 glasses/day
- Hypothyroidism
- Fish or shellfish allergy
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Ian Lanza, Ph.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available