The Effect of Intranasal Vasoconstrictor Medications on Hemodynamic Parameters: A Randomized Double-blind, Placebo-controlled Trial.
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-006312
NCT ID: NCT02285634
Sponsor Protocol Number: 14-006312
About this study
Inclusion Criteria:
- Healthy volunteers over the age of eighteen that have been recently dismissed from the Emergency Department at Mayo Clinic Hospital, Saint Marys Campus.
- We will recruit a convenience sample of 100 patients from the Emergency Department who have completed their Emergency Department evaluation and treatment and are being discharged to home with non-painful conditions.
Exclusion Criteria:
- We will exclude persons under the age of eighteen
- Vulnerable populations (pregnant patients and prisoners)
- Those with an allergy to any of the study agents
- Those with acute pain
- Those using antihypertensive or antiarrhythmic agents
- Those with significant cardiopulmonary comorbidities (namely history of arrhythmia, coronary artery disease, hypertension, and heart failure)
- Those with concomitant use of MAO-Inhibitors
- Those with a diagnosis of angle closure glaucoma or BPH
- Those with a history of cerebrovascular disease
- As well as those with a history of previous nasal surgery or known nasal anatomic abnormalities.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Healthy volunteers over the age of eighteen that have been recently dismissed from the Emergency Department at Mayo Clinic Hospital, Saint Marys Campus.
- We will recruit a convenience sample of 100 patients from the Emergency Department who have completed their Emergency Department evaluation and treatment and are being discharged to home with non-painful conditions.
Exclusion Criteria:
- We will exclude persons under the age of eighteen
- Vulnerable populations (pregnant patients and prisoners)
- Those with an allergy to any of the study agents
- Those with acute pain
- Those using antihypertensive or antiarrhythmic agents
- Those with significant cardiopulmonary comorbidities (namely history of arrhythmia, coronary artery disease, hypertension, and heart failure)
- Those with concomitant use of MAO-Inhibitors
- Those with a diagnosis of angle closure glaucoma or BPH
- Those with a history of cerebrovascular disease
- As well as those with a history of previous nasal surgery or known nasal anatomic abnormalities.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Tobias Kummer, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available