A Study of Overgrowth in Small Intestine Bacteria from Long Term Use of Medication Limiting Stomach Acid
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-000008
Sponsor Protocol Number: 14-000008
About this study
The purpose of this study is to find out if taking long term medication to limit stomach acid results in the overgrowth of small intestine bacteria
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Age18-75 years
- Able to provide consent
- Endoscopically documented esophagitis or newly diagnosed Barrett’s Esophagus
- Starting PPI therapy for at least 12 months (must be free of PPI use within the past year)
Exclusion Criteria
- Non-fluent in English
- Non-US residents
- Institutionalized or incarcerated
- Has a legal guardian
- Current, recent (within 1 week) or recurrent antibiotic therapy
- Diabetics or other individuals in whom glucose administration would be contraindicated
- Past Small Intestine Bacterial Overgrowth
- History of altered small intestinal anatomy (e.g. Roux en Y anatomy) that would affect ability to detect SIBO via GBT
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Conor Loftus, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available