Genetic Mutations and Environmental Exposure in Young Patients With Retinoblastoma and in Their Parents and Young Healthy Unrelated Volunteers
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
NCT ID: NCT00690469
Sponsor Protocol Number: AEPI05N1
About this study
This laboratory study is looking at genetic mutations and environmental exposure in young patients with retinoblastoma and in their parents and young healthy unrelated volunteers. Gathering information about gene mutations and environmental exposure may help doctors learn more about the causes of retinoblastoma in young patients.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Cases must meet the following criteria:
- Diagnosed with sporadic retinoblastoma (RB) on or after 07/01/2006
- No familial retinoblastoma
- Have permission of physician to contact the parents
- Diagnosed and/or treated at a Children's Oncology Group (COG) institution or *Wills Eye Hospital
- Controls must meet 1 of the following criteria:
- Mother of a child with unilateral RB
- Father of a child with bilateral RB
- Age-matched non-blood-related child if possible
- Must reside in the U.S. or Canada
- Must have telephone in the home
- Biological parent speaks English or Spanish
- Concurrent treatment on a therapeutic trial is NOT required
More information
Publications
Publications are currently not available