Perfusion Assessment of Wound Closure Techniques in Primary Total Knee Arthroplasty

Overview

About this study

This study will assess which of the three most common methods of wound closure in primary total knee arthroplasty (staples, interrupted vertical mattress, or running subcuticular suture) provide the best wound vascular perfusion. This can be achieve by using SPY intra-operative vascular angiography, which is commonly used in clinical practice to assess perfusion of wound closure at the clinic. By understanding the differences in perfusion afforded by different closure techniques, surgeons will then be able to select the technique that optimizes this parameter so as to avoid complications such as tissue necrosis, wound dehiscence, or infection.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • ≥ 18 years old
  • Primary diagnosis of osteoarthritis
  • Surgical indication for index total knee arthroplasty

Exclusion Criteria:

  • Previous surgery about the knee
  • Systemic corticosteroid use
  • Active infection of any kind or chronic infection with HIV, Hepatitis C, or Syphilis

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Robert Trousdale, M.D.

Closed for enrollment

More information

Publications

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Additional contact information

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