A Study Using Genetic Panel to Assist in Diagnosis of Hereditary Young Onset Dementia
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Sponsor Protocol Number: 14-009952
About this study
The purpose of this study is to use a specific gene panel to assist in the diagnosis of a hereditary form of young onset dementia.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Have a dementia syndrome with onset prior to age 60 years
- Felt to be degenerative on clinical grounds
- Have had a standard Mayo Clinic dementia evaluation including
- Structural brain imaging
- Complete blood counts
- Metabolic panel
- Thyroid function
- Vitamin B12 levels
- Through June 30, 2015, additional testing will be required given the young age of onset including
- spinal fluid examination for possible chronic meningoencephalitic causes of progressive cognitive decline
- electroencephalography
- Additionally, any patients with positive biomarker tests (amyloid or fluorodeoxyglucose PET, CSF biomarkers) will be preferred
- After June 30 these additional tests will be encouraged but no longer required to maximize enrollment during the funding period
- Patients and families will have to agree to disclosure of results
More information
Publications
Publications are currently not available