A Study to Assess if Contrast-Enhanced Ultrasound Positively Influences the Selection of Biopsy Sites When Evaluating Transplant Kidneys
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 14-009240
NCT ID: NCT02625428
Sponsor Protocol Number: 14-009240
About this study
The purpose of this pilot study is to investigate whether contrast-enhanced ultrasound (CEUS) may help evaluate segmental differences in renal perfusion better than doppler ultrasound and thus help direct a biopsy to the most abnormal part of the renal cortex.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Ability to provide informed consent
- Male and female >18 years
- Patients undergoing renal transplant ultrasound-guided percutaneous biopsy within 14 months post transplant including patients undergoing biopsy to evaluate a recent rise in serum creatinine, (so called "for cause" biopsies) and patients undergoing routine protocol (surveillance) biopsies without other evidence of renal dysfunction
Exclusion Criteria
- Pregnant women or women who are nursing an infant are not able to participate in this study
- Known patent foramen ovale (PFO)
- Significant heart disease
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Jeffry Kriegshauser, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available