A Study of Pre-Conditioning Prior to Surgery to Improve Functional and Clinical Outcomes in Patients with Aortic Stenosis

Overview

About this study

The purpose of this study is to evaluate whether simple cardiac exercise interventions to improve physical performance before transcatheter aortic valve replacement (TAVR) surgery improves outcomes after TAVR.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Eligibility for TAVR
  • SPPB < 9
  • Able to exercise
  • Able to come for follow-up visits
  • Able to give informed consent

 

Exclusion Criteria

  • New York Heart Association (NYHA) Class III/IV congestive heart failure (CHF)
  • Presyncope or syncope as presentation
  • Acute coronary syndrome
  • Unable to exercise
  • Dementia
  • Sustained ventricular arrhythmia
  • Stroke with neurological deficit
  • Advanced Parkinson's
  • Participated in an exercise program

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Eau Claire, Wis.

Mayo Clinic principal investigator

Deaglan O'Cochlain, M.D.

Closed for enrollment

Rochester, Minn.

Mayo Clinic principal investigator

Mandeep Singh, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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