A Study of Magnetic Resonance Elastography to Measure Heart Muscle Stiffness in Patients with Hypertrophic Cardiomyopathy
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 15-002100
Sponsor Protocol Number: 15-002100
About this study
The purpose of this study is to use magnetic resonance elastography to assess heart muscle stiffness in patients with hypertrophic cardiomyopathy compared to normal subjects.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Normal subjects
- Age ≥ 18 years
- Normal heart sounds
- Normal breath sounds
- Measured systolic blood pressure < 140 mm Hg
- Measured diastolic blood pressure < 90 mm Hg
- Hypertrophic cardiomyopathy
- A clinically-indicated cardiac MRI ordered for evaluation of hypertrophic cardiomyopathy
Exclusion Criteria
- Normal Subjects
- History of angina, coronary artery disease, heart failure, hypertension, hypertensive medication, valvular heart disease, congenital heart disease, diabetes
- Contraindications or relative contraindications to MRI scanning, namely internal defibrillators or pacemakers, cerebral aneurysm clips, severe claustrophobia, and pregnancy or suspected pregnancy (self-reported)
- Hypertrophic cardiomyopathy
- History of prior myocardial infarction, myocarditis, or prior heart transplantation
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Philip Araoz, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available