A Study to Determine the Microbial Population of the Intestines in Patients with Active or Treated Inactive Eosinophilic Esophagitis
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 16-001097
Sponsor Protocol Number: 16-001097
About this study
The purpose of this study is to collect stool samples and determine the intestine microbe environment in patients who have active or treated inactive eosinophilic esophagitis.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Clinical diagnosis of Eosinophilic Esophagitis
- Age 18-65
- Has clinically indicated endoscopy/ biopsies for Eosinophilic Esophagitis
- Healthy volunteers of age and sex matched controls from a biobank
Exclusion Criteria
- Prior history of abdominal surgeries (except appendectomy and cholecystectomy)
- Known diagnosis of inflammatory bowel disease, microscopic colitis, celiac disease, atopic dermatitis, active asthma or other inflammatory conditions
- Antibiotic use within the past 4 weeks (they can be enrolled after a four week washout period and subsequent use during the 6 month study duration does not exclude them)
- Bowel preparation for colonoscopy within the past week
- Vulnerable adults
- Age ≥ 66
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator David Katzka, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available