[Impedance Measurement for Non-Erosive Reflux Disease
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 16-007762
NCT ID: NCT02997527
Sponsor Protocol Number: 16-007762
About this study
This study is being done to determine if people with and without GERD or trouble swallowing have increased esophageal mucosa impedance (food getting into the esophageal tissue).
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Adults ages 18-90
- Patients with heartburn and no hiatal hernia undergoing clinically indicated endoscopy
- Patients with heartburn and a hiatal hernia > 3cm undergoing clinically indicated endoscopy
- Patients undergoing clinically indicated upper endoscopy for indications other than dysphagia or GERD
- Patients with reflux symptoms, a normal appearing esophagus on clinically indicated endoscopy undergoing clinically indicated ambulatory pH/impedance testing.
Exclusion Criteria:
- Previous gastric or esophageal surgery.
- Use of proton pump inhibitors 1 month prior to the study
- Patients on anticoagulation other than aspirin or clopidogrel
- Presence of erosive esophagitis or Barrett's esophagus
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator David Katzka, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available