A Study to Identify the Molecular Basis of Pulmonary Vascular Disease and to Discover Biological Measurements of the Disease and Therapeutic Responses
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 15-008490
NCT ID: NCT02980887
Sponsor Protocol Number: PVDOMICS
About this study
The purpose of this study is to identify the molecular basis of various forms of heart and lung disease, particularly those that have varying degrees of pulmonary hypertension, pulmonary vascular remodeling, and right ventricular dysfunction.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Ages > 18 years
- Referred for right heart catheterization for
- Further evaluation of known PVD
- Risk of PVD due to established cardiac disease or pulmonary disease
- Able to perform complete diagnostic testing listed subsequently
- Cardiac catheterization
- Echo
- Exercise test
- PFT's
- ECG
- Chest CT
- Quality of life questionnaires
- Ventilation/perfusion scan
- Cardiac MRI
- Body composition bioimpedance
- Sleep study
- Signed informed consent to perform required testing for the protocol
Exclusion Criteria
- Dialysis dependent renal function
- In the clinician's opinion, too ill to perform the protocol testing
- Pregnant or nursing
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Robert Frantz, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available