Identification of risk factors and risk markers in Patients with Cavernous Malformations

Overview

About this study

This study aums to determine whether various markers of vascular stability are predictive of clinical events (intracerebral hemorrhage or focal neurologic deficits). The study will alos determine the prevalence of vitamin D deficiency in patients with cavernous malformation and determine if vitamin D deficiency correlates with presenting classification (Hemorrhage, Focal Neurologic Deficit, Seizure, Asymptomatic state) or natural history (hemorrhage risk).

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients with cavernous malformations of the spine or brain identified radiologically or pathologically

Exclusion Criteria:

  • Patients will be excluded if their cavernous malformation has already been removed and they have no remaining CM. 

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Kelly Flemming, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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