Nicotinamide Riboside Supplementation and Aging on Altitude Acclimatization
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 16-003485
Sponsor Protocol Number: 16-003485
About this study
The focus of the project is to determine if nicotinamide riboside (NR) supplementation improves the acclimatization process to high altitude. In addition, we will investigate the interaction with aging with a focus on cardio-pulmonary adaptations.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age 18-90 years
- Non-smokers
- Generally healthy
- English speaking
- Willing to fund their trip and travel costs to climb Mount Kilimanjaro
- Signed form stating they have received approval for participation in this study from their primary care provider
Exclusion Criteria:
- Unable to hike 5-10 miles/day (no orthopedic limitations)
- Moderate to severe lung disease
- Insulin dependent diabetes
- Kidney disease/ renal insufficiency
- Known history of high altitude pulmonary edema (HAPE) or high altitude cerebral edema (HACE)
- Pregnant women
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Bruce Johnson, Ph.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available