Effect of Fasting, Endogenous GLP-1 Secretion on B-cell Response to Intravenous Glucose
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 15-006016
Sponsor Protocol Number: 15-006016
About this study
The purpose of this study is to determine the effect of GLP-1 in priming β-cells for insulin secretion.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- BMI 18 – 35 Kg/M2
- Fifteen patients with normal glucose tolerance and fifteen with impaired fasting glucose
- Participants will be in good health
- Stable weight
- Not engaged in regular vigorous exercise
- No history of diabetes or of prior therapy with antidiabetic medication
- No history of chronic disease
- No prior abdominal surgery other than cholecystectomy or appendectomy
Exclusion Criteria:
- Subjects < 20 years of age or > 65 years of age
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Adrian Vella, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available