Olfactory and Sinonasal Epithelium as Cell Source of Neural Progenitors and Autologous Constructs
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 15-009696
Sponsor Protocol Number: 15-009696
About this study
The goals of the study are to develop protocols for growing cells isolated from the nasal epithelium and fat tissue. This will be used to help grow nerve-related tissue as well as cartilage, epithelial cells, muscle cells, or other cells that are present in the head and neck region. The goal is to generate a large number of cells that could be used for constructing tissue that can be implanted for structural and functional reconstruction.
The development of such methods is a step in our goal to rehabilitate patients with cancer, trauma, or other debilitating neurological diseases that lose function and structure in the head and neck area. The cells isolated from your tissues will not be used for developing implants but will help with experiments to establish the protocols needed to cultivate cells and develop the implant.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- This study will enroll patients who are undergoing endoscopic endonasal skull base procedures where nasal tissue and fat is taken as standard of care. Tissue that is removed for creating surgical access, or is left behind after skull base reconstruction is usually discarded as "surgical waste". The research will involve use of this tissue.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Devyani Lal, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available