CNS Autoantibody and Inflammatory Marker Investigation in Catatonia
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 15-002519
Sponsor Protocol Number: 15-002519
About this study
The overall objective of this study is to compare seroprevalence rates, titers of central nervous system (CNS) autoantibodies, and inflammatory markers in catatonic patients.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age 18-60, male or female, any race/ethnicity
- Diagnosis of catatonia utilizing two screening tools, 1) the 23-item Bush-Francis Catatonia Rating Scale (BFCRS), and 2) the DSM-5 catatonic symptoms:3 out of 12 symptoms present [2, 33]
Exclusion Criteria:
- Inability to speak English
- Inability or lack of willingness to obtain informed consent from patient or legal authorized representative.
- Involuntary treatment or hospitalization
- Out patients with active suicidality as defined by a score of 2 or higher on question # 18 of the Inventory for Depressive Symptoms (IDS)
- Active or unstable medical condition as evaluated by clinical interviewer
- Presence of co-morbid Axis I or Axis II disorder that is the primary diagnosis and current focus of treatment
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
More information
Publications
Publications are currently not available