Estimating Reference Change Value for Tests of Platelet Function

Overview

About this study

The purpose of this study is to define the change or “delta” in platelet function tests that represents a significant change in patient condition, to facilitate antiplatelet agent titration and monitoring as part of a standardized anticoagulation protocol for patients on mechanical circulatory support.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Mayo employees who have previously volunteered/participated in the Department of Laboratory Medicine and Pathology normal value (normal donor) program.

Exclusion Criteria:

  • Pregnant women
  • Diagnosed bleeding abnormality
  • History of easy bruising
  • Previous thrombosis or major bleeding episode 
  • Surgery or an infection treated with antibiotics within the previous six weeks 
  • Taking estrogens or oral contraceptives
  • Volunteers who have consumed over the counter pain relievers within 4 days of a blood draw, or aspirin-containing products within 10 days of a blood draw

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Brad Karon, M.D., Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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