Vision-Related Quality of Life in Fuchs Endothelial Corneal Dystrophy
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-005327
Sponsor Protocol Number: 14-005327
About this study
The goal of this study is to understand when in the course of disease vision-related quality of life becomes impaired, and to determine associations between quality of life and visual and optical factors in the disease.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Subject population:
500 subjects with Fuchs dystrophy;
100 subjects with normal corneas.
Inclusion Criteria:
Subjects will be recruited regardless of lenticular status, i.e. phakic subjects without or with cataracts, and pseudophakic subjects, will be enrolled.
Fuchs dystrophy will be defined as the presence of central or paracentral corneal guttae, and normal subjects will have absence of any central or paracentral corneal guttae.
Exclusion Criteria:
Subjects with comorbidities that may affect vision-related quality of life, such as corneal scarring (from any cause except Fuchs dystrophy) or ectasia, macular disease, optic neuropathy, or amblyopia, and with the exception of cataract (which is very prevalent with increasing age).
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Sanjay Patel, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available