A Study of the Effects of Limb Cooling on Essential Tremor Using Electrophysiological Measurements

Overview

About this study

The purpose of this study is to determine the effects of limb cooling on an essential tremor of that limb with a forearm cold pack, measuring the results by electrophysiological testing.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

This study has been completed

Inclusion Criteria

  • Clinical diagnosis of E.T. for at least a year by a movement disorder neurologist
  • A +2 or worse action or kinetic tremor of one or both upper limbs involving at least the forearm and/or hand
  • Age 18 to 95 years

Exclusion Criteria

  • (+) sensory loss in the upper extremities
  • Dermatologic lesions in upper extremities (e.g. skin cancer, eczema, fresh or healing wounds, abrasions, acne, pustules, abscesses, or skin rash)
  • Known history of sensitivity to cold (i.e., cold urticaria)
  • Known peripheral vascular disease
  • Raynaud's phenomenon
  • Scleroderma

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Virgilio Evidente, M.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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