Impact of Liver INR, an Alternatively Calibrated INR, on MELD Scores in Chronic Liver Disease Patients
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 15-000442
Sponsor Protocol Number: 15-000442
About this study
The aim of this study is to evaluate the impact of liver International normalize ratio (INR) (in comparison to conventional INR) on MELD scores in chronic liver disease patients.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- CLD patients with a full spectrum of disease severity (categorized by Child-Pugh score)
Exclusion Criteria:
- Exclude use of drugs known to interfere with coagulation tests (heparin, warfarin, direct thrombin inhibitors, direct factor Xa inhibitor, lupus coagulant)
- Extrahepatic malignancy
- Other known hemostatic disorders
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Rong He, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available