Prophylactic Benzodiazepine versus Reinstitution of Maintenance Antiseizure Drugs following Ictal SPECT
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 17-000780
Sponsor Protocol Number: 17-000780
About this study
The primary aim of this study is to compare the pre- and post-single photon emission computed tomography (SPECT) seizure frequency following an IV benzodiazepine protocol versus reinstitution of maintenance antiseizure drugs (ASDS).
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age >18
- Admitted to Mayo Clinic Florida EMU
- Patients with medically refractory focal epilepsy
Exclusion Criteria:
- Patients with generalized epilepsy
- Patients with epileptic seizures coexisting with psychogenic non-epileptic seizures
- Patients with previous history of SISCOM related complication
- Patients who are allergic to the radioisotope (Technetium Tc99m Exametazime)
- Pregnant women
- Patients who refuse to participate in the study
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator William Tatum, D.O. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available