Multi-phase Dual Energy for Quantitative and Radiologic Evaluation of Chronic Liver Disease
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-002169
Sponsor Protocol Number: 14-002169
About this study
The purpose of this study is to assess the combined impact of post-processing methods that quantify potential biomarkers of chronic liver disease (AEF, fECS) and that improve iodine signal (vMono+) on detecting liver fibrosis and hepatic masses or esophageal varices, in comparison to routine contrast-enhanced liver CT.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Known or suspected chronic liver disease with or without hepatocellular carcinoma.
- Informed consent to research contrast-enhanced, dual energy CT and unenhanced MR scan with elatography.
- Serum creatine, bilirubin and INR ordered for clinical purposes.
- A negative pregnancy test is required, if the subject is a female of child bearing age
Exclusion Criteria:
- Any contraindication for MR imaging (MRI) including pacemakers, cochlear implants, and certain spinal stimulation devices.
- Insufficient MR image quality for quantitative analysis.
- A female subject with a positive pregnancy test
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Joel Fletcher, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available