Circulating Angiogenic Cells and Diabetic Vascular Disease
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-002361
Sponsor Protocol Number: 14-002361
About this study
This study is being done to determine the roles that several molecules play in the repair of injured cells that line your blood vessels.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Healthy subjects (fasting plasma glucose <100 mg/dL, two-hour glucose during the 75-g OGTT <140 mg/dL, and A1C <5.7%)
- Non-smokers and non-obese (BMI£28),
- Males/females (18-45 years old).
- Candidates will be free of systemic diseases and conditions known to affect vascular or endothelial function (i.e. hypertension, hypercholesterolemia, coronary artery disease, cancer, inflammatory disease, or smoking).
- T1DM patients will be non-smoker, free of complications (such as retinopathy, nephropathy, neuropathy, coronary heart disease, and hypertension).
Exclusion Criteria:
- Candidates will be considered ineligible if they have active infection, trauma, or exposure to any invasive
- medical procedures within 2 weeks before collecting blood.
- The subjects who have medications including “over-the-counter” medications within 2 weeks before collecting blood, will also be excluded (diabetic subjects
- will be treated with prescribed medications only).
- Subjects will be asked to refrain from caffeine on the day of the study visit and also refrain from alcohol use on the day before the study visit and the day of the visit.
- Subjects will also be asked to fast for 8 hours before they come in for the blood draw.
- All female subjects must
- have a negative pregnancy test in order to participate in the study.
- Subjects who are breast-feeding will be excluded.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
More information
Publications
Publications are currently not available