Inclusion Criteria:

• Any patient with a diagnosis of AAV.
• Potential subjects will be identified on the basis of their being scheduled for evaluation in the pulmonary vasculitis clinic.
• All patients scheduled in the clinic will be recruited, either in advance of their appointment (via telephone contact or posted written materials) or at the time of their clinical visit (via a face-to-face meeting). 
• Community outreach will not be feasible for this rare disease, but again, all patients scheduled in the pulmonary vasculitis clinic are eligible for recruitment. 
• Patients admitted to the hospital with a diagnosis of AAV are also eligible for participation.  
• Informed consent will be obtained via usual verbal and written procedures in the clinic itself.  Consent will be obtained by clinical research personnel.

For disease controls of interest

Inclusion Criteria:

• Diagnosis of interstitial lung disease (ILD), autoimmune renal disease, or rheumatologic condition.
• Willingness and ability to complete blood draws.

Exclusion Criteria:

• Age <18.

For healthy controls

Inclusion Criteria:

• Male or female, age 18 to 85.
• Willingness and ability to complete blood draws.

Exclusion Criteria:

• History of or currently have an autoimmune disease.
• History of diagnosis and treatment for cancer within the last 5 years except for non-melanoma skin cancers or breast or genitourinary cancer in situ.

Note: Other protocol defined Inclusion/Exclusion Criteria may apply.

Eligibility last updated 6/25/2024. Questions regarding updates should be directed to the study team contact.