Assessing the Utility of Quantitative Fecal Fat Studies to Diagnose Small Intestinal Bacterial Overgrowth (SIBO)
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 14-003950
Sponsor Protocol Number: 14-003950
About this study
The purpose of this study is to understand how the results from a fecal fat test compare to results from the duodenal aspirate culture which was collected during a recent clinical EGD. The goal is to determine whether this less expensive, non-invasive test that can be performed at home can potentially be used in place of an EGD with fluid collection and culture, particularly to monitor response to treatment.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Patients undergoing EGD with quantitative duodenal aspirate culture will be identified
- A brief screening questionnaire will be administered. If diarrhea (defined as >3 BM/s day at least 25% of the time, or Bristol stool form 6-7 at least 25% of the time) is present, then individuals will be asked to participate.
- Written informed consent will be required.
Exclusion Criteria:
- Age <18 years
- Medical condition precluding questionnaire completion (e.g. dementia, mental retardation, stroke, etc.)
- Condition requiring legal guardianship
- Non-US residents or prisoners
- Non-English speaking
- Diagnoses that result in steatorrhea (e.g. short gut, untreated celiac disease)
- Pregnancy (pregnant women will not have a routine EGD performed clinically)
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Yuri Saito Loftus, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available