A Study of Repetitive Transcranial Magnetic Stimulation as a Treatment for Depression Added to Standard Care
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 10-000401
NCT ID: NCT01115699
Sponsor Protocol Number: 10-000401
About this study
The purpose of this study is to systematically investigate the use of repetitive transcranial magnetic stimulation (rTMS) as an added treatment for patients who have depression that is not decreasing with standard care.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Depressive symptoms have not remitted during participation in the "Pharmacokinetics and Pharmacodynamics of Citalopram and Escitalopram" study or the "Pharmacokinetics and Pharmacodynamics of Duloxetine" study
- Must be able to continue to take same dose of duloxetine through the course of the study
Exclusion Criteria
- A history of failure to respond to Electroconvulsive Therapy (ECT)
- Any metal in the head (except in mouth)
- Implanted medication pump or cardiac pacemaker
- Has had prior brain surgery
- Has unprovoked seizure disorder or family history of treatment resistant epilepsy
- Pregnancy
- Psychiatric hospitalization within the past two weeks
- Suicide attempt with hospitalization within past three months
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator David Mrazek, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available