A Study to Improve Treatment of Clostridium Difficile Infection and using Information Technology to Improve the Care of Patients with Severe Clostridium Difficile Infection
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 10-002633
Sponsor Protocol Number: 10-002633
About this study
The purpose of the study is to ascertain the efficacy of implementation of standard treatment guidelines for the treatment of C. difficile infection based on disease severity and number of instances of this infection.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
The criteria to diagnose “definite” cases of CDI in patients with appropriate clinical presentation of diarrhea (> 3 loose stools / day) or unexplained abdominal pain and leucocytosis, and any one of the following:
- Clostridium difficile positive by polymerase chain reaction in stool in a patient with diarrhea
- Endoscopic finding of pseudomembranous colitis
- Endoscopic or surgical biopsies showing pseudomembranous colitis without another cause
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Darrell Pardi, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available