A Study to Determine How Corneal Transparency is Affected in Fuchs Dystrophy
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 12-004579
Sponsor Protocol Number: 12-004579
About this study
The purpose of this study is to determine how corneal transparency is affected in Fuchs dystrophy, and if a measure of corneal transparency (haze) can help grade the severity of the disease.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
Fuchs group
- Presence of central or paracentral corneal guttae
- Any age (expected range will be 40-90)
- Any sex or race
Normal group
- Absence of central or paracentral corneal guttae
- Ages 51-80 (to match the predominant age of subjects with Fuchs dystrophy)
- Any sex or race
Exclusion Criteria:
- Any corneal disease (except Fuchs dystrophy in the Fuchs group)
- Previous ocular surgery (except for cataract surgery with posterior chamber intraocular lens in the Fuchs dystrophy group)
- Use of topical ocular medications, expect artificial tears
- Glaucoma or ocular hypertension
- Systemic diseases known to affect the cornea, e.g. diabetes
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Sanjay Patel, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available