Autism Spectrum Disorder: Birth Cohort 1976-2000, Epidemiology and Adult Status
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 12-004334
Sponsor Protocol Number: 12-004334
About this study
Autism Spectrum Disorders (ASDs) are lifelong neurodevelopmental conditions with mostly unknown etiology that have a huge impact on affected individuals and their families, and are a major public health concern. Significant gaps exist in the knowledge of ASD frequency and its possible rising trend. Detailed characterization of ASD cases ASD subtypes is sparse, and potential risk factors (etiologies) are still unknown. We will study certain risk factors like perinatal risk factors and family history (parents, siblings) of psychiatric disorders. Knowledge about adult outcomes of ASD cases identified in childhood is almost non-existent. ASD-associated medical costs are high, yet information to improve cost-effective medical management is lacking. A unique set of circumstances, including population-based birth cohort of all children born 1976-2000 to mothers residing in Olmsted County, MN (N=43,934), access to detailed medical records for every child in the birth cohort (Rochester Epidemiology Project-REP), and Olmsted County Healthcare Expenditure and Utilization Database (OCHEUD) provide the infrastructure to successfully work on this project. The knowledge achieved through this combined retrospective and prospective epidemiologic approach will substantially advance scientific/clinical knowledge about ASD.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Individuals who were born in Rochester, Minnesota between 1976 and 2000 who we have identified, during childhood, as having autism spectrum disorders (ASDs) for a total of 43,215 with 1,297 children
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Maja Katusic, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available