Intraventricular Nicardipine for Aneurysmal Subarachnoid Hemorrhage Related Vasospasm: Assessment on Clinical Outcomes of Stroke by 30 & 90 Days
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 10-008337
Sponsor Protocol Number: 10-008337
About this study
The purpose is to study the effects of intraventricular nicardipine, a vasodilatory agent, on VP and secondary outcomes of stroke and functional outcome at 30 and 90 days compared to those not treated with this agent.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Aneurysmal or arteriovenous malformation (AVM)-related subarachnoid hemorrhage, with CTA or digital subtraction angiogram evidence of intracranial aneurysm or AVM
- Patients with EVD placed by clinical criteria
- Patients age 18 years or older
- Documented or abstracted Modified Rankin Scores (MRS) and Glasgow Outcomes Scale (GOS) scores during admission and at 30 (or if 30 day data not available, then mRS at discharge) and 90 days
Exclusion Criteria:
- Patients being treated with intraventricular antibiotics for bacterial meningitis related vasospasm
- Patients without arterial bleeding subarachnoid hemorrhage (non-aneurysmal, non-AVM) or vasospasm due to another cause
- Pregnant patients
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator William Freeman, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available