Characterizing the Inflammatory Marker Profiles of Free Flap Reconstructive Head and Neck Surgery
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 17-000315
Sponsor Protocol Number: 17-000315
About this study
The purpose of this study is to characterize the inflammatory markers of free flap reconstructive head and neck surgery in humans by analyzing specific inflammatory markers in blood samples from patients with the hope of better understanding free flap physiology in order to eventually improve patient outcomes.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Patient is between ages 18 and 65
- Must be undergoing reconstructive head and neck surgery following cancer excision
- Patient must be undergoing either a radial forearm free flap, fibular free flap, or scapular system free flap performed by the Otolaryngology-Head and Neck Surgery (Mayo Clinic, RST) department.
Exclusion Criteria:
- Anyone who is currently taking immunomodulatory or immunosuppressant medications
- Anyone with a history of autoimmune disease
- Anyone with a current diagnosis of type II diabetes mellitus or chronic kidney disease
- Anyone who is pregnant
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Jeffrey Janus, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available