A Study of Normative Data for Bone-conducted VEMP Responses (amplitude, latency, threshold, asymmetry, signal-to-noise ratio) in Patients Without Vestibular Dysfunction
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 17-008506
Sponsor Protocol Number: 17-008506
About this study
The purpose of this study is to develop a set of normative data for bone-conducted VEMP responses (amplitude, latency, threshold, asymmetry, signal-to-noise ratio) in patients without vestibular dysfunction, and to assess the reliability and replicability of these responses.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Adult or children subjects with present and symmetrical cervical and ocular VEMPs elicited with air-conduction stimuli. Subjects will not be excluded due to additional otologic presentation (e.g., hearing loss, tinnitus).
- Patients who have undergone a unilateral cochlear implantation and device activation referred by our Cochlear Implant Clinic.
- Typically-developing children without balance disorders will serve as participants for this investigation.
Exclusion Criteria:
- Patients less than 6 years of age.
- Subjects will be excluded if they are unable to maintain muscle contraction sufficient to record responses.
- Patients with significant orthopedic and/or neurological deficits that influence balance or mobility performance, and prevent reliable completion of the testing procedures will be excluded from the study.
- Additional handicap that would limit the patient from being able to follow study instructions.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Devin McCaslin, Ph.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available