Genetic Variation, Stress, and Functional Outcomes After Stroke Rehabilitation
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 17-004437
Sponsor Protocol Number: 17-004437
About this study
The purpose of this research study is to examine how certain genes and lifetime and ongoing stress may impact rehabilitation and recovery after stroke.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Age ≥18 years
- Stroke that is ischemic in etiology or intracerebral hemorrhage, onset 2-10 days prior, and radiologically confirmed on either CT or MRI.
- Able to provide responses to study assessments, determined by whether subjects can answer 2 simple screening questions.
- Able to communicate in English.
- Reasonable expectation patient can participate in study visits through month 12.
- Reasonable likelihood that patient will receive standard of care rehabilitation therapy after discharge.
Exclusion Criteria:
- Expected survival is <1 year.
- Moderate-severe disability prior to stroke (pre-stroke modified Rankin scale score >2).
- Had a major brain or nerve disease that was active immediately prior to the stroke.
- Was hospitalized for a mental health problem in the prior 24 months.
- History of a symptomatic stroke in the 90 days prior to the index stroke.
- History of moderate-severe traumatic brain injury, operationally defined as a traumatic event accompanied by loss of consciousness for >30 minutes.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator James Meschia, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available