A Study to Evaluate the Use of Pharmacogenomics in the Perioperative Period to Guide Drug Therapy in Patients Undergoing Total Knee Arthroscopy
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 17-006577
NCT ID: NCT03579121
Sponsor Protocol Number: 17-006577
About this study
The purpose of this study is to look at the use of pharmacogenomic data in the perioperative period to guide drug therapy in patients undergoing total knee arthroscopy.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Patients 18 to 80
- Patients undergoing primary total knee arthroplasty
- Patients must understand and provide written informed consent and HIPAA authorization prior to initiation of any study-specific procedures.
Exclusion Criteria
- Patients with a current diagnosis of chronic pain
- Patients requiring narcotics for greater than one week prior to surgery
- Patients with chronic kidney disease with a pre-op creatinine greater than 1.5
- Patient preference or need for spinal anesthesia rather than general anesthesia
- Patient planned for robotic surgical approach
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Molly Kraus, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available