A Study Next Generation Sequencing (NGS) that May Help Identify Useful Genetic Information in Patients with Genetic Kidney Disease

Overview

About this study

The purpose of this study approach aims to identify exomic alterations that contribute to the development of kidney disease.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria

  • Patient must have evidence of a genetic renal condition or a suspected genomic renal disorder for which previous genetic or other testing has not provided a diagnosis, or be a biological family member of such a patient.
  • Patient/family member is willing to undergo session(s) with a genomic counselor (GC).
  • Patient must understand and provide written informed consent and HIPAA authorization prior to initiation of any study-specific procedures. For a pediatric patient and patient without capacity to consent for him/herself, parents or legal guardians must understand and provide written informed consent and HIPAA authorization prior to initiation of any study-specific procedures.
  • Participants of any age are eligible to participate.
  • Pregnant women may participate in this research study. Should research results be returned that would have implications for offspring the participant will be offered genetic counseling.

Exclusion Criteria 

  • Patient who has an uncontrolled concurrent illness including psychiatric illness, or situations that would limit compliance with the study requirements or the ability to willingly give written informed consent, and who does not have a legal guardian who will take responsibility for ensuring compliance with study requirements and can provide consent on his/her behalf.
  • Family member participants will not be eligible for research study if the proband/surrogate declines participation.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Marie Hogan, M.D., Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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