A Study Next Generation Sequencing (NGS) that May Help Identify Useful Genetic Information in Patients with Genetic Kidney Disease
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 17-005255
Sponsor Protocol Number: 17-005255
About this study
The purpose of this study approach aims to identify exomic alterations that contribute to the development of kidney disease.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
- Patient must have evidence of a genetic renal condition or a suspected genomic renal disorder for which previous genetic or other testing has not provided a diagnosis, or be a biological family member of such a patient.
- Patient/family member is willing to undergo session(s) with a genomic counselor (GC).
- Patient must understand and provide written informed consent and HIPAA authorization prior to initiation of any study-specific procedures. For a pediatric patient and patient without capacity to consent for him/herself, parents or legal guardians must understand and provide written informed consent and HIPAA authorization prior to initiation of any study-specific procedures.
- Participants of any age are eligible to participate.
- Pregnant women may participate in this research study. Should research results be returned that would have implications for offspring the participant will be offered genetic counseling.
Exclusion Criteria
- Patient who has an uncontrolled concurrent illness including psychiatric illness, or situations that would limit compliance with the study requirements or the ability to willingly give written informed consent, and who does not have a legal guardian who will take responsibility for ensuring compliance with study requirements and can provide consent on his/her behalf.
- Family member participants will not be eligible for research study if the proband/surrogate declines participation.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Marie Hogan, M.D., Ph.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available