Hypertensive Pregnancy Disorders and Future Coronary Artery Disease

Overview

About this study

The purpose of the study is to determine if:

  • A history of hypertensive pregnancy disorders (HPD), in general, and preeclampsia, in particular, compared to normotensive pregnancies, confers an increased risk for coronary artery disease (CAD) after controlling for traditional risk factors.
  • A history of HPD, in general, and preeclampsia, in particular, compared to normotensive pregnancies, is associated with more severe atherosclerotic disease at the time of the diagnosis of CAD.
  • A history of HPD, in general, and preeclampsia, in particular, compared to normotensive pregnancies, increases the risk for a composite outcome of subsequent CAD, atrial fibrillation, heart failure, stroke, and cardiovascular death in women with incident CAD.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  1. Parous women with a history of cornary artery disease (CAD)
  2. Women without CAD

Exclusion Criteria:

  1. Women without pregnancies

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Vesna Garovic, M.D., Ph.D.

Closed for enrollment

Contact information:

Vesna Garovic M.D., Ph.D.

(507)266-1944

Garovic.Vesna@mayo.edu

More information

Publications

Publications are currently not available