Study Using Ultrasound to Evaluate High-Frequency Percussive Ventilation Based Proton Therapy Motion Mitigation

Overview

About this study

The purpose of this study is to evaluate the effectiveness of the high frequency percussive ventilation (HFPV) technique and demonstrate tolerable and reproducible thoracic immobilization with less than 5 mm residual motion.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Male and female adult volunteers (18 years of age or older).

Exclusion Criteria: 

We will exclude volunteers who have any history of the following conditions:

  • Asthma.
  • COPD.
  • Pneumothoraxes.
  • Hemoptysis.
  • Fractured ribs.
  • Unstable chest, panic and anxiety disorder, requirement for supplemental oxygen.
  • Volunteers who are otherwise healthy.
  • Pregnant or plan to be pregnant.
  • Unable to sign informed consent due to cognitive impairment.
  • Currently or has a history of cigarette or cannabis usage.
  • Any disorder that may cause respiratory neuromuscular weakness.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status

Rochester, Minn.

Mayo Clinic principal investigator

Erik Tryggestad, Ph.D.

Closed for enrollment

More information

Publications

Publications are currently not available

Additional contact information

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Phone: 800-664-4542 (toll-free)

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