Study to Assess Cardiac Dyspnea Using Exercise Cardiac Magnetic Resonance as a Diagnostic Tool
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Jacksonville, Florida: 18-005354
NCT ID: NCT03951779
Sponsor Protocol Number: 18-005354
About this study
The purpose of this study is to assess cardiac dyspnea using exercise cardiac magnetic resonance as a diagnostic tool.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria:
- Consecutive patients aged ≥ 18 years old.
- Suspected cardiac dyspnea.
- Scheduled to undergo right heart catheterization as dictated by a comprehensive examination.
- Echocardiography will be included for enrollment.
Exclusion Criteria:
- Age < 18 years old.
- Pregnancy.
- Mechanical ventilation.
- Acute or chronic renal failure (creatinine clearance < 30 ml/min or requiring renal replacement therapy).
- Inability to perform MRI (i.e., claustrophobia, severe obesity (>150 kg), device incompatible with MRI).
- Inability to exercise.
- Significant arrhythmia that precludes adequate ECG-gating for the MRI (i.e., atrial fibrillation with highly variable cycle lengths).
- Prior heart or lung transplantation.
- Left ventricular systolic (ejection fraction < 50%) or diastolic failure (based on Framingham criteria for heart failure with preserved ejection fraction).
- Significant left-sided valvular disease (≥ moderate aortic stenosis, mitral stenosis, aortic regurgitation, mitral regurgitation) or prior valve surgery.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Jacksonville, Fla.
Mayo Clinic principal investigator Brian Shapiro, M.D., M.A. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available