A Study to Establish an International Multicenter Registry of Pancreatic Cysts

Overview

About this study

The purpose of this study is to identify and characterize specific symptoms and cyst characteristics, as predictors of the grade of malignancy and long-term behavior of PCN/IPMNs.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • High to moderate clinically suspected IPMN following the consensus guidelines criteria: presence of a dilated main pancreatic duct ([MPD] ≥ 5 mm) or a cystically dilated branch duct (≥5 mm) or Individuals with a pancreatic cyst (either newly or previously diagnosed, or previously operated upon).
  • Cyst surveillance is warranted, according to the treating physician.
  • Age ≥ 18 years old.
  • Informed consent.
  • High resolution imaging technique (MRI, CT scan, or endoscopic ultrasonography [EUS]) performed as a baseline examination.

Exclusion Criteria:

  • Patients who do not meet the above inclusion criteria.
  • History of chronic pancreatitis.
  • Suspected pseudocyst (simple, thin walled cyst that developed in the course of acute (necrotising) pancreatitis, as documented by sequential imaging studies).
  • Suspected serous cystadenoma (typical microcystic lesion with lobulated outlines and a calcified central scar, and cyst fluid CEA levels < 5 ng/ml).
  • Von Hippel-Lindau disease.
  • Limited life expectancy (< 2 years).

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Michael Wallace, M.D.

Open for enrollment

Contact information:

Stacey Pecenka BAS, M.P.H.

(904) 953-4261

Pecenka.Stacey@mayo.edu

More information

Publications

Publications are currently not available