Overview

About this study

The purpose of this study is to:

1. To describe the clinical presentation of patients with resistance to local anesthetics.

2. To consent subject for a blood draw and send the sample to local BAP core facility for DNA isolation.

3. To send the DNA sample to the Sequencing Core at Mayo Rochester to sequence the participants’ exome including the sodium channel genes.

4. Analyze the patient’s and family members’ whole exome sequence to identify novel mutations associated with the patient’s clinical presentation.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Participating Mayo Clinic locations

More information