A Study of Topical Antibiotics in Chronic Rhinosinusitis
Overview
Tab Title Description
Study type
InterventionalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
NCT ID: NCT03673956
Sponsor Protocol Number: 18-006599
About this study
The purpose of this study is to describe the results of antibiotic resistant organisms after the use of topical antibiotics in the treatment of chronic rhinosinusitis.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria
All participants in the study must meet all of the following inclusion criteria to participate in this study:
- Diagnosed with chronic rhinosinusitis who have undergone previous functional endoscopic sinus surgery including at minimum maxillary antrostomy and anterior ethmoidectomy.
- Active mucopurulence on endoscopic examination with corresponding culture demonstrating pathogenic bacterial growth.
- Completion of written informed consent.
- No prior enrollment into this study.
- Refractory to maximal medical therapy.
Exclusion Criteria:
Candidates meeting any of the following exclusion criteria at baseline will be excluded from study participation:
- Patient has not had prior endoscopic sinus surgery consisting of at minimum bilateral maxillary antrostomy and anterior ethmoidectomy.
- Patient is currently being treated with oral antibiotics.
- Patient has been treated with oral or topical antibiotics within the past 14 days.
- Participation in an investigational drug study simultaneously with participation in this study.
- Concurrent use of oral steroids.
- Known to currently be pregnant.
More information
Publications
Publications are currently not available