Inclusion Criteria:

Step 0 Eligibility Criteria

• Age ≥ 18 years old
• Patient must have a prior or current cancer diagnosis (e.g., solid tumor or hematologic malignancy) that fits into any one of the following categories:
  • Patient is receiving active treatment (defined as current treatment or treatment within the past 6 weeks) for metastatic cancer. Eligible treatment types are chemotherapy, immunotherapy, monoclonal antibody therapy (e.g., rituximab, trastuzumab, cetuximab), targeted therapy (e.g., BRAF/MEK inhibitor, EGFR inhibitor), endocrine therapy, or radiation therapy
  • Patients is receiving adjuvant treatment for non-metastatic (Stage I-III) cancer and has received intravenous chemotherapy, immunotherapy, targeted therapy, or radiation therapy within the past 6 weeks
  • Patient has received an allogenic stem cell transplant or CAR-T cell or other modified cellular therapy at any time
  • Patient is currently receiving treatment or prophylaxis for Graft vs. Host Disease
  • Patient has received an autologous bone marrow transplant within the past 2 years
• Testing for SARS CoV-2
  • Patient must be undergoing or have undergone testing for SARS CoV-2.
  • Patients with prior negative SARS CoV-2 test(s) are eligible if they are being tested again. 
  • Patients with prior positive SARS CoV-2 test(s) more than 14 days prior to enrollment are not eligible.
• HIV-infected patients are eligible
• Patients with brain metastases are eligible
• Co-enrollment on other clinical trials (for cancer or for COVID-19) is allowed.

Step 1 Eligibility Criteria

• Positive SARS CoV-2 test within the 14 days prior to enrollment to Step 1
  • Patient must have a documented positive SARS CoV-2 test. The positive test results must have been received no earlier than 14 days prior to enrollment to Step 1.
  • The test must have been ordered by a doctor’s office, hospital, or department of public health.
  • Any specimen source (e.g., nasopharyngeal swab, oropharyngeal swab, etc.) is allowable for the SARS CoV-2 test.

Exclusion Criteria:

• Patients < 18 years old.