A Study to Evaluate the Spectral Topogram to Predict Osteoporosis and Osteopenia

Overview

About this study

The Photon Counting Detector Computed Tomography (PCD-CT) Spectral Topogram can be resolved into multispectral components given the ability of photon counting detectors. This modality, therefore, has the ability to quantify bone mineral density and may be an alternative to dual-energy X-ray absorptiometry (DEXA) scan in the routine clinical screening of high-risk individuals for osteoporosis.  PCD-CT Spectral Topogram may, therefore, be an opportunistic way to increase osteoporosis screening for individuals undergoing CT, particularly at-risk populations.

 

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Male and female patients aged 18 years or more.
  • Patients with IBD, Celiac disease, and a history of receiving a liver transplant, or potential conditions or on drugs that may predispose them to osteoporosis.
  • Ability to undergo a research DEXA scan on Gonda 2.
  • Patients able and willing to sign informed consent.

Exclusion Criteria:

  • Patients not meeting inclusion criteria will be excluded.
  • Patients unable or unwilling to provide informed consent.
  • Patients with metal artifacts affecting the regions of interest.
  • Pregnancy.
  • Body mass index of more than 30.

 

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Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Joel Fletcher, M.D.

Closed for enrollment

Contact information:

Joel Fletcher M.D.

Fletcher.Joel@mayo.edu

More information

Publications

Publications are currently not available