Dielectric Tissue Characterization

Overview

About this study

In this prospective feasibility study we will measure the dielectric properties of various gastrointestinal tissue types using freshly excised resection specimens. Patients undergoing gastrointestinal endoscopy and clinically indicated endoscopic resection will be approached for study participation. Immediately following resection, the specimen will be imaged using volumetric laser endomicroscopy for tissue characterization and precise localization of complex permittivity measurements. The resection specimen will then be submitted for routine histopathological assessment. Our group has previously used a similar framework for the study of various image enhancement technologies without impacting the care of our patients. In order to adequately measure the dielectric properties of healthy tissue, we also propose performing measurements in freshly resected gastrointestinal surgical specimens.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Patients over the age of 18 years.
  • Ability to provide informed consent.
  • Patients scheduled for gastrointestinal endoscopy and clinically indicated resection through our advanced endoscopy practice at Mayo Clinic Saint Mary Hospital, Alfred 6 Endoscopy Unit; or
  • Patients undergoing clinically indicated surgical resection of the gastrointestinal tract (esophagus, stomach, small bowel, colon).

Exclusion Criteria:     

  • Patients in who endoscopic or surgical resection is contraindicated.
  • Patients who are pregnant.

Eligibility last updated 8/25/21. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Cadman Leggett, M.D.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Kevin Buller

(507) 255-4803

Buller.Kevin@mayo.edu

More information

Publications

Publications are currently not available