A Study to Establish a Research Tissue Bank for Myeloproliferative Neoplasms
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Scottsdale/Phoenix, Arizona: 21-006268
Sponsor Protocol Number: MPN-RC 106
About this study
The purpose of this study is to credential novel therapeutic approaches which can then be transitioned to the clinic for near-term mechanism based clinical trials in this research consortium. There is a need for new treatments for myelofibrosis (MF) patients based on laboratory insight into disease pathogenesis. We will use primary patient samples to understand how different genetic mutations contribute to MF development and to test novel treatment approaches.
Participation eligibility
Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.
Inclusion Criteria - Eligible patients must meet criteria 1 OR 2:
- Newly diagnosed subjects diagnosed with Philadelphia chromosome negative myeloproliferative neoplasms (MPN) polycythemia vera (PV), prefibrotic myelofibrosis (Pre-PMF), overt primary myelofibrosis (PMF), essential thrombocythemia (ET), and myeloproliferative neoplasm blast phase (MPN-blast phase) or MPN-Unclassifiable (MPN-U).
- Patients previously treated for an MPN.
- Signed informed consent is required from each patient at the time of enrollment.
Exclusion Criteria:
- Patients currently participating in experimental treatment arms of MPN-RC protocols, or other experimental treatment protocols.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
Contact |
Scottsdale/Phoenix, Ariz.
Mayo Clinic principal investigator Jeanne Palmer, M.D. |
Open for enrollment |
Contact information:
Cancer Center Clinical Trials Referral Office
855-776-0015
|
More information
Publications
Publications are currently not available