Nailfold Blood Vessel Imaging for Disorders of Vessel Inflammation

Overview

About this study

The overall goal of this research study is to examine the use of Nailfold Videocapillaroscopy (NVC) for prognostication of patients with Small Vessel Vasculitis (SVV).

Nailfold videocapillaroscopy (NVC) is a simple and noninvasive tool utilized by rheumatologists for monitoring of systemic sclerosis, dermatomyositis, and Raynaud’s phenomenon{Jung, 2013 #5}. A capillaroscope is utilized to view the nailfold capillaries and evaluate for evidence of small vessel abnormalities, which can be seen with the aforementioned disorders.

 

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria:

  • Age ≥ 18 years

Exclusion Criteria: 

  • Dialysis dependence.
  • Type 2 diabetes.
  • Diagnosis of scleroderma.
  • Diagnosis of Raynaud’s phenomenon or disease.
  • Recent hand trauma or manicure (< 2 weeks).
  • Routine use of vibratory tools.
  • History of acrocyanosis or erythromyelgia.
  • Previous diagnosis of a bleeding disorder.
  • Diagnosis of psoriasis.
  • Diagnosis of anti-phospholipid syndrome.
  • Exposure to toluene or benzoyl.

Eligibility last updated 01/20/2022. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Jacksonville, Fla.

Mayo Clinic principal investigator

Florentina Berianu, M.D.

Closed-enrolling by invitation

What is this? (?)
"Close"
Not open to everyone who meets the eligibility criteria, but only those invited to participate by the study team.

Contact information:

Megan Sullivan M.D.

(701) 640-5808

Sullivan.Megan2@mayo.edu

More information

Publications

Publications are currently not available