IMAGING CORE: NAPS2 DaT Core
Overview
Tab Title Description
Study type
ObservationalDescribes the nature of a clinical study. Types include:
- Observational study — observes people and measures outcomes without affecting results.
- Interventional study (clinical trial) — studies new tests, treatments, drugs, surgical procedures or devices.
- Medical records research — uses historical information collected from medical records of large groups of people to study how diseases progress and which treatments and surgeries work best.
Study IDs
Site IRB
- Rochester, Minnesota: 22-002055
About this study
The objectives of this study are:
- To conduct research on RBD as a prodromal manifestation of DLB, PD, and MSA to address several of the NAPA ADRD priorities for LBD research as well as similar priorities for PD and MSA. Investigate RBD occurring in prodromal synucleinopathy.
- To enroll RBD participants and matched control participants for longitudinal, standardized collection of clinical, PSG, genetic, biofluid, and neuroimaging data.
- To analyze collected data against longitudinal clinical outcomes to refine scales and develop /analyze biomarkers to optimally design clinical trials.
- To share data, samples, and methods for use by the scientific community.
- To interact with NIH, other scientific groups on RBD and overt synucleinopathies, industry partners, patients, and other groups.
- To prepare for large-scale clinical trials.
The Neuroimaging Core is responsible for imaging operations at 10 NAPS sites, Harmonization and maintenance of the DaTscan protocols, quality control and storage of the imaging data, analysis and sharing of the imaging data.
Participating Mayo Clinic locations
Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.
| Mayo Clinic Location |
Status |
|
Rochester, Minn.
Mayo Clinic principal investigator Val Lowe, M.D. |
Closed for enrollment |
|
More information
Publications
Publications are currently not available