Etiology, Prevention and Therapy Navigation of Cancer

Overview

About this study

The purpose of this study is to evaluate the integration of cancer pan-genetic testing into a cancer clinical practice and understand both its use and effect in “real world” practice conditions.

Participation eligibility

Participant eligibility includes age, gender, type and stage of disease, and previous treatments or health concerns. Guidelines differ from study to study, and identify who can or cannot participate. There is no guarantee that every individual who qualifies and wants to participate in a trial will be enrolled. Contact the study team to discuss study eligibility and potential participation.

Inclusion Criteria - Group A Germline and Somatic Testing:

  • Has Mayo Clinic medical record number.
  • Confirmed cancer diagnosis which is either recurrent, relapsed, refractory, metastatic, or advanced.
  • Participant aware of cancer diagnosis.
  • Able to provide informed consent.
  • ≥ 18 years old.
  • Ability to provide blood, saliva, bone marrow aspirate or hair follicle sample.
  • Ability to provide archived tissue.
    • NOTE: if tissue unavailable participant may still enroll onto the study for the germline collection.

Exclusion Criteria:

  • Individuals who have situations that would limit compliance with the study requirements.
  • Institutionalized (i.e., Federal Medical Prison).
  • Prior germline genetic testing with a 100+ multi-gene panel within the last 1 year of enrollment AND/OR
  • Prior somatic tissue (250+ gene) testing within the prior 3 months of enrollment.
    • NOTE: Women, who are pregnant, or planning to become pregnant, can take part in this study.

Inclusion Criteria - Group B Germline Testing Only:

  • Has Mayo Clinic medical record number.
  • Confirmed cancer diagnosis.
  • Participant aware of cancer diagnosis.
  • Able to provide informed consent.
  • ≥ 18 years old.
  • Ability to provide blood, saliva, or hair follicle sample.

Exclusion Criteria:

  • Individuals who have situations that would limit compliance with the study requirements.
  • Institutionalized (i.e. Federal Medical Prison).
  • Prior germline genetic testing with a 100+ multi-gene panel within the last 1 year of enrollment.

Eligibility last updated 12/28/23. Questions regarding updates should be directed to the study team contact.

Participating Mayo Clinic locations

Study statuses change often. Please contact the study team for the most up-to-date information regarding possible participation.

Mayo Clinic Location Status Contact

Rochester, Minn.

Mayo Clinic principal investigator

Mrinal Patnaik, M.B.B.S.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

Jacksonville, Fla.

Mayo Clinic principal investigator

Jeremy Jones, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

Scottsdale/Phoenix, Ariz.

Mayo Clinic principal investigator

Niloy Jewel Samadder, M.D.

Open for enrollment

Contact information:

Cancer Center Clinical Trials Referral Office

(855) 776-0015

More information

Publications

Publications are currently not available